Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | PBK | Q96KB5 | 3/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629599 | 0.78 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL1554160 | 0.76 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL1554161 | 0.75 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| Hydrochloric Acid SCHEMBL8576071 | 0.75 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL8627261 | 0.74 | SMN1; SMN2 (0.42) | ADORA2A | |
| SCHEMBL8569992 | 0.73 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL8576057 | 0.73 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL8629605 | 0.73 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL2458459 | 0.72 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL1552957 | 0.71 | PDE4D (0.54) | PDE4APDE4BPDE4CPDE4DPBK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |