Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | HPGD | P15428 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625170 | 0.86 | KDM4E (0.52) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL14845200 | 0.81 | FOXO1 (0.52) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL14845181 | 0.79 | KDM4E (0.55) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL8483940 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL15999528 | 0.78 | FOXO1 (0.52) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL8111305 | 0.78 | FOXO1 (0.52) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL8486917 | 0.78 | LMNA (0.35) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL8160866 | 0.78 | LMNA (0.53) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL15999546 | 0.78 | KDM4E (0.54) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL25069270 | 0.77 | FOXO1 (0.65) | ALDH1A1HPGDKDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684942-B1 | METHOD FOR PREPARING QUINOLINE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | HOECHST CELANESE CORP (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5430152-A | Heating aminoarylester in presence of chlorosulfonic acid, oleum | HOECHST CELANESE CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |