Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629507 | 0.92 | KCNMA1 (0.36) | MAPTALDH1A1LMNAGAANPSR1 | |
| SCHEMBL8627401 | 0.89 | AVPR2 (0.39) | AVPR2PAX8RAB9ARECQLMAPT | |
| SCHEMBL8634668 | 0.88 | AVPR2 (0.51) | AVPR2MAPTLMNACASP3CASP7 | |
| SCHEMBL8627677 | 0.87 | AVPR2 (0.38) | AVPR2PAX8RAB9ARECQLMAPT | |
| SCHEMBL8630678 | 0.83 | AVPR2 (0.38) | AVPR2PAX8RAB9ARECQLMAPT | |
| SCHEMBL8632674 | 0.83 | AVPR2 (0.51) | AVPR2MAPTLMNATP53 | |
| SCHEMBL8627398 | 0.82 | AVPR2 (0.37) | AVPR2PAX8RAB9ARECQLMAPT | |
| SCHEMBL8630767 | 0.82 | AVPR2 (0.41) | AVPR2MAPTALDH1A1GAACASP3 | |
| SCHEMBL8627538 | 0.81 | KCNMA1 (0.36) | MAPTALDH1A1LMNAGAANPSR1 | |
| SCHEMBL4685314 | 0.80 | AVPR2 (0.42) | AVPR2PAX8RAB9ARECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |