Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3074145 | 0.89 | CYP4F2 (0.61) | CYP4F2CYP4A11CASP1ALDH1A1KDM4E | |
| SCHEMBL3849724 | 0.85 | PDE4A (0.42) | ALDH1A1KDM4ETSHRKMT2ASMN1; SMN2 | |
| SCHEMBL3983100 | 0.85 | ALDH1A1 (0.49) | CYP4F2CYP4A11CASP1ALDH1A1KDM4E | |
| SCHEMBL3582809 | 0.85 | CASP1 (0.49) | CYP4F2CYP4A11CASP1ALDH1A1KDM4E | |
| SCHEMBL9370802 | 0.83 | KDM4E (0.50) | CYP4F2CYP4A11ALDH1A1KDM4ETSHR | |
| SCHEMBL9383978 | 0.83 | CASP1 (0.47) | CYP4F2CYP4A11CASP1ALDH1A1KDM4E | |
| SCHEMBL2782609 | 0.83 | OPRK1 (0.48) | CYP4F2CYP4A11CASP1ALDH1A1KDM4E | |
| SCHEMBL16702899 | 0.83 | ALDH1A1 (0.49) | CASP1ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL2086658 | 0.83 | CASP1 (0.47) | CYP4F2CYP4A11CASP1ALDH1A1KDM4E | |
| SCHEMBL6559833 | 0.82 | TSHR (0.46) | CYP4F2CYP4A11ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846684-A2 | Process for producing 2-halo-nicotinic acid derivatives and precursors thereto | REILLY INDUSTRIES, INC. (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5493028-A | Processes for producing 2-Halo-nicotinic acid derivatives and precursors thereto | REILLY INDUSTRIES, INC. (US) | 1996-02-20 | — | — | US | disclosed |
| EP-0633880-A1 | PROCESSES FOR PRODUCING 2-HALO-NICOTINIC ACID DERIVATIVES AND PRECURSORS THERETO | REILLY INDUSTRIES, INC. (US) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993018005-A2 | PROCESSES FOR PRODUCING 2-HALO-NICOTINIC ACID DERIVATIVES AND PRECURSORS THERETO | REILLY INDUSTRIES, INC. (US) | 1993-09-16 | — | — | WO | disclosed |