Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | OGG1 | O15527 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420212 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL693383 | 0.86 | TDP1 (0.49) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL8207302 | 0.85 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL8416828 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL8206250 | 0.80 | MAPT (0.47) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL8418751 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL8202557 | 0.79 | SLC6A9 (0.48) | ALDH1A1HPGDKDM4ETDP1MEN1 | |
| SCHEMBL8202190 | 0.79 | MAPK1 (0.43) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL8418428 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL7294511 | 0.78 | PTGDR2 (0.61) | ALDH1A1HPGDKDM4ETSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719760-B1 | Naphthalene derivatives and their use as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1999-09-22 | — | — | EP | claimed |
| EP-0719760-A1 | Naphthyloxyacetic acid derivatives and their use as PGW2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | claimed |