Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | BRD1 | O95696 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635104 | 0.92 | PPARA (0.39) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8629955 | 0.89 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8634282 | 0.88 | EDNRA (0.38) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8633047 | 0.87 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8630041 | 0.87 | CCR4 (0.40) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8631639 | 0.87 | KMT2A (0.41) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8634385 | 0.86 | ACLY (0.42) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8629730 | 0.86 | MAPT (0.45) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8627950 | 0.85 | MAPT (0.38) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8635365 | 0.85 | MAPT (0.44) | MAPTMEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |