Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | KAT7 | O95251 | 1/20 | 0.38 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630562 | 0.91 | CCR4 (0.42) | CCR4PTGS1PTGS2PDE4APDE4B | |
| SCHEMBL8629955 | 0.91 | MAPT (0.46) | MAPTPTGS1PTGS2POLBMEN1 | |
| SCHEMBL8627950 | 0.88 | MAPT (0.38) | MAPTPTGS1PTGS2POLBMEN1 | |
| SCHEMBL8634282 | 0.87 | EDNRA (0.38) | MAPTPTGS1PTGS2POLBMEN1 | |
| SCHEMBL8628055 | 0.87 | MAPT (0.40) | MAPTPTGS1PTGS2POLBMEN1 | |
| SCHEMBL8630525 | 0.86 | CCR4 (0.41) | CCR4MAPTPTGS2MEN1KMT2A | |
| SCHEMBL8631438 | 0.86 | CYP1A2 (0.46) | CCR4MAPTPTGS2POLBKMT2A | |
| SCHEMBL8634385 | 0.86 | ACLY (0.42) | MAPTPTGS1PTGS2POLBMEN1 | |
| SCHEMBL8629928 | 0.85 | PTGS2 (0.43) | MAPTPTGS2MEN1KMT2AKDM4E | |
| SCHEMBL8630479 | 0.84 | CCR4 (0.41) | CCR4PTGS1PTGS2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |