Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628055 | 0.92 | MAPT (0.40) | PPARAALDH1A1MAPTTSHRPTGS2 | |
| SCHEMBL8633047 | 0.89 | MAPT (0.40) | ALDH1A1MAPTTSHRPTGS2KDM4E | |
| SCHEMBL8631745 | 0.89 | PTGS2 (0.41) | PPARAMAPTPTGS2MEN1KMT2A | |
| SCHEMBL8630945 | 0.88 | PPARA (0.39) | PPARAPTGS2PI4KBACLYHTR6 | |
| SCHEMBL8630562 | 0.87 | CCR4 (0.42) | PPARAPTGS2PI4KBTP53PTGS1 | |
| SCHEMBL8631639 | 0.87 | KMT2A (0.41) | ALDH1A1MAPTTSHRPTGS2KDM4E | |
| SCHEMBL8629560 | 0.86 | PTGS2 (0.49) | ALDH1A1MAPTTSHRPTGS2KDM4E | |
| SCHEMBL8629545 | 0.86 | NPC1 (0.41) | PPARAALDH1A1PTGS2KDM4EACLY | |
| SCHEMBL8631722 | 0.85 | PPARA (0.41) | PPARAPTGS2PI4KBACLYHTR6 | |
| SCHEMBL8629013 | 0.85 | PPARA (0.39) | PPARAMAPTPTGS2PI4KBACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |