Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | F10 | P00742 | 11/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633695 | 0.90 | F10 (0.39) | PTGS2PTGS1F10F2PRSS1 | |
| SCHEMBL8628758 | 0.88 | HTR7 (0.40) | PTGS2PTGS1F10PTGDR2NR1H3 | |
| SCHEMBL8633221 | 0.87 | PTGS2 (0.38) | PTGS2PTGS1F10F2PRSS1 | |
| SCHEMBL8631669 | 0.86 | PTGES2 (0.38) | PTGS2PTGS1F10F2PRSS1 | |
| SCHEMBL8632316 | 0.86 | PTGS1 (0.40) | PTGS2PTGS1F10F2PRSS1 | |
| SCHEMBL8635053 | 0.84 | PTGS1 (0.44) | PTGS2PTGS1F10PTGDR2NR1H3 | |
| SCHEMBL8628074 | 0.82 | F10 (0.40) | PTGS2PTGS1F10F2PRSS1 | |
| SCHEMBL7779901 | 0.82 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL8631607 | 0.82 | PTGS1 (0.38) | PTGS2PTGS1F10F2PRSS1 | |
| SCHEMBL8630541 | 0.82 | PTGS2 (0.57) | PTGS2PTGS1F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |