SCHEMBL8628124

SCHEMBL8628124

CCP(c1cc(C)c(N(C)C)c(C)c1)c1cc(C)c(N(C)C)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9322371 0.75 MEN1 (0.34) GAAMEN1POLBKMT2A
SCHEMBL5080137 0.72 ALDH1A1 (0.38)
SCHEMBL637775 0.71 MEN1 (0.36) GAAMEN1POLBKMT2A
SCHEMBL636826 0.71 MEN1 (0.32) GAAMEN1POLBKMT2A
Hydrochloric Acid SCHEMBL28448881 0.70 ALDH1A1 (0.36)
SCHEMBL19496402 0.69 MEN1 (0.41) GAAMEN1POLBKMT2A
Dimethylamine SCHEMBL8628126 0.67 ALDH1A1 (0.33)
SCHEMBL60535 0.66 RAPGEF4 (0.43) GAAMEN1POLBKMT2A
SCHEMBL28184328 0.64 RAPGEF4 (0.41) GAAMEN1POLBKMT2A
Hydrochloric Acid SCHEMBL3680590 0.64 RAPGEF4 (0.41) GAAMEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0848697-A1 PROCESS FOR THE HYDROGENATION OF IMINES Novartis AG (CH) 1998-06-24 EP claimed
WO-1997005095-A1 PROCESS FOR THE HYDROGENATION OF IMINES NOVARTIS AG (CH) 1997-02-13 WO claimed
EP-0850241-A1 IRIDIUM-DIPHOSPHINE COMPLEXES AND PROCESS FOR THE HYDROGENATION OF IMINES Novartis AG (CH) 1998-07-01 EP disclosed
WO-1997005150-A1 IRIDIUM-DIPHOSPHINE COMPLEXES AND PROCESS FOR THE HYDROGENATION OF IMINES NOVARTIS AG (CH) 1997-02-13 WO disclosed