Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | NAT1 | P18440 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629976 | 0.91 | L3MBTL1 (0.51) | L3MBTL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8631355 | 0.89 | L3MBTL1 (0.44) | L3MBTL1MEN1KMT2AKDM4ERXFP1 | |
| SCHEMBL8629853 | 0.88 | MEN1 (0.45) | L3MBTL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8635392 | 0.88 | L3MBTL1 (0.49) | L3MBTL1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8632682 | 0.88 | KDM1A (0.46) | L3MBTL1MEN1KMT2AHTTKDM4E | |
| SCHEMBL8628831 | 0.87 | LRRK2 (0.50) | L3MBTL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8633701 | 0.85 | KMT2A (0.48) | L3MBTL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8627990 | 0.85 | HPGD (0.41) | L3MBTL1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8631696 | 0.85 | SLC40A1 (0.42) | L3MBTL1LRRK2EDNRBEDNRAMAPT | |
| SCHEMBL8627699 | 0.83 | MAPK14 (0.40) | L3MBTL1MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |