Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 3/20 | 0.32 |
| ▸ | PPOX | P50336 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680895 | 0.65 | AVPR2 (0.41) | AVPR2PDK1PDK2PDK3PDK4 | |
| SCHEMBL8628978 | 0.65 | AVPR2 (0.47) | AVPR2PDK1PDK2PDK3PDK4 | |
| SCHEMBL8628984 | 0.64 | AVPR2 (0.46) | AVPR2PDK1PDK2PDK3PDK4 | |
| SCHEMBL8628980 | 0.62 | AVPR2 (0.47) | AVPR2PDK1PDK2PDK3PDK4 | |
| SCHEMBL5480924 | 0.58 | AVPR2 (0.46) | AVPR2PDK1PDK2PDK3PDK4 | |
| SCHEMBL7352110 | 0.57 | HDAC1 (0.73) | AVPR2PDK1PDK2PDK3PDK4 | |
| SCHEMBL8809305 | 0.56 | KDM4E (0.58) | AVPR2PDK1PDK2PDK3PDK4 | |
| SCHEMBL17653852 | 0.55 | HDAC1 (0.51) | PDK1PDK2PDK3PDK4KCNQ2 | |
| SCHEMBL3401840 | 0.55 | HPGD (0.55) | AVPR2TSHRMAPTALDH1A1HTT | |
| SCHEMBL10165521 | 0.55 | NOTUM (0.45) | PDK1PDK2PDK3PDK4KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |