Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628729 | 0.86 | ERN1 (0.33) | SLC6A4SLC6A2HPGDSMN1; SMN2KMT2A | |
| SCHEMBL8625853 | 0.82 | HPGD (0.32) | SLC6A4SLC6A2P2RX7ATMHPGD | |
| SCHEMBL8625850 | 0.82 | HPGD (0.32) | SLC6A4SLC6A2P2RX7ATMHPGD | |
| SCHEMBL8629071 | 0.78 | ALDH1A1 (0.42) | NPC1HPGDRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8631726 | 0.77 | ERN1 (0.35) | MAPT | |
| SCHEMBL8632344 | 0.72 | DGAT1 (0.38) | ATMNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8628727 | 0.72 | MEN1 (0.32) | HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8628725 | 0.72 | MEN1 (0.32) | HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8629068 | 0.71 | ADRA1D (0.34) | NPC1HPGDRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8629066 | 0.71 | ADRA1D (0.34) | NPC1HPGDRAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705243-B1 | BETA-AMINOVINYL KETONES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR PREPARING BETA DIKETONES | RHONE POULENC AGROCHIMIE (FR) | 1998-06-24 | — | — | EP | disclosed |
| US-5684206-A | CONDENSING METHYL ORGANO KETONE WITH A BENZONITRILE IN PRESENCE OF STRONG BASE | RHONE-POULENC ARGOCHIMIE (FR) | 1997-11-04 | — | — | US | disclosed |