Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MARS1 | P56192 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631669 | 0.91 | PTGES2 (0.38) | PTGS1PTGS2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8634661 | 0.91 | PTGS2 (0.45) | PTGS1PTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL8629795 | 0.88 | PTGS2 (0.40) | PTGS1PTGS2F10PTGDR2NR1H3 | |
| SCHEMBL8630521 | 0.87 | PTGS1 (0.45) | HTR7HTR1AHTR2APTGS1PTGS2 | |
| SCHEMBL8631203 | 0.86 | PTGDR2 (0.46) | HTR7HTR1AHTR2APTGS1PTGS2 | |
| SCHEMBL8633221 | 0.86 | PTGS2 (0.38) | PTGS1PTGS2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7777321 | 0.85 | PTGS2 (0.47) | HTR7HTR1AHTR2APTGS1PTGS2 | |
| SCHEMBL8631606 | 0.82 | HTR7 (0.39) | HTR7HTR1AHTR2APTGS1PTGS2 | |
| SCHEMBL8631831 | 0.82 | HTR7 (0.39) | HTR7HTR1AHTR2APTGS1PTGS2 | |
| SCHEMBL8629984 | 0.82 | PTGS2 (0.44) | HTR7HTR1AHTR2APTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |