Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.46 |
| ▸ | CHUK | O15111 | 3/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.42 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9361146 | 0.85 | ESR1 (0.42) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL8630238 | 0.77 | RAB9A (0.57) | CASP3SENP8SENP7SENP6HSD17B10 | |
| SCHEMBL28563204 | 0.77 | NOTUM (0.50) | NPC1KDM4EALDH1A1RAB9AHPGD | |
| SCHEMBL5267951 | 0.74 | ALOX15 (0.47) | HSD17B10NPC1KDM4EALDH1A1RAB9A | |
| SCHEMBL15392970 | 0.73 | NOTUM (0.36) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL5945934 | 0.73 | NOTUM (0.54) | — | |
| SCHEMBL3613332 | 0.73 | ALDH1A1 (0.46) | HSD17B10NPC1KDM4EALDH1A1RAB9A | |
| SCHEMBL9737555 | 0.73 | NPC1 (0.64) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL352664 | 0.71 | NPC1 (0.50) | HSD17B10NPC1KDM4EALDH1A1RAB9A | |
| SCHEMBL11324245 | 0.70 | L3MBTL1 (0.55) | CASP3SENP7HSD17B10NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |
| US-4201779-A | 7[(2-Amino-thiazol-4-yl)glyoxylamido]-cephem derivatives and processes for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-06 | — | — | US | disclosed |
| US-4016159-A | BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |