Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8758119 | 0.95 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTLMNAACLY | |
| SCHEMBL8631663 | 0.90 | MAPK14 (0.46) | ACLYMAPK14AAK1PTGS2PTGS1 | |
| SCHEMBL8634594 | 0.89 | FFAR4 (0.39) | ALDH1A1MAPTLMNAPOLBMAPK14 | |
| SCHEMBL8629284 | 0.88 | CCR4 (0.39) | ALDH1A1MAPTLMNAPOLBMAPK14 | |
| SCHEMBL8627699 | 0.85 | MAPK14 (0.40) | ALDH1A1LMNAMAPK14MEN1KMT2A | |
| SCHEMBL8633701 | 0.84 | KMT2A (0.48) | ALDH1A1KDM4EMAPTLMNAPOLB | |
| SCHEMBL8629853 | 0.83 | MEN1 (0.45) | ALDH1A1KDM4EMAPTLMNAMEN1 | |
| SCHEMBL8630886 | 0.82 | MCL1 (0.45) | ALDH1A1HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8633621 | 0.82 | MAPK14 (0.39) | ALDH1A1LMNAMAPK14MEN1KMT2A | |
| SCHEMBL8629976 | 0.81 | L3MBTL1 (0.51) | ALDH1A1KDM4EMAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |