Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SGK1 | O00141 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634594 | 0.91 | FFAR4 (0.39) | MAPK14FFAR4LRRK2MEN1KMT2A | |
| SCHEMBL8631663 | 0.87 | MAPK14 (0.46) | MAPK14MAP2K4PTGS2 | |
| SCHEMBL8634943 | 0.86 | MAP2K4 (0.44) | MAPK14MAP2K4LRRK2MEN1KMT2A | |
| SCHEMBL8629853 | 0.85 | MEN1 (0.45) | FFAR4LRRK2MEN1KMT2ATDP1 | |
| SCHEMBL8630886 | 0.85 | MCL1 (0.45) | FFAR4LRRK2MEN1KMT2ATDP1 | |
| SCHEMBL8629227 | 0.85 | ALDH1A1 (0.43) | MAPK14MEN1KMT2APTGS2L3MBTL1 | |
| SCHEMBL8631355 | 0.84 | L3MBTL1 (0.44) | MAPK14MAP2K4LRRK2MEN1KMT2A | |
| SCHEMBL8633621 | 0.84 | MAPK14 (0.39) | MAPK14MAP2K4MEN1KMT2ATDP1 | |
| SCHEMBL8629976 | 0.84 | L3MBTL1 (0.51) | FFAR4LRRK2MEN1KMT2AL3MBTL1 | |
| SCHEMBL8633591 | 0.83 | L3MBTL1 (0.43) | FFAR4LRRK2MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |