Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631696 | 0.89 | SLC40A1 (0.42) | MAPTL3MBTL1TP53 | |
| SCHEMBL8629976 | 0.88 | L3MBTL1 (0.51) | KMT2AMAPTGPR55CNR1CNR2 | |
| SCHEMBL8627678 | 0.88 | MAPT (0.51) | KMT2AGAAMAPTMEN1ALDH1A1 | |
| SCHEMBL8629853 | 0.87 | MEN1 (0.45) | KMT2AGAAMAPTL3MBTL1MEN1 | |
| SCHEMBL8630471 | 0.86 | SMN1; SMN2 (0.43) | KMT2AGAAMAPTMEN1SMN1; SMN2 | |
| SCHEMBL8631355 | 0.86 | L3MBTL1 (0.44) | KMT2AMAPTL3MBTL1MEN1POLB | |
| SCHEMBL8633591 | 0.85 | L3MBTL1 (0.43) | KMT2AMAPTGPR55L3MBTL1MEN1 | |
| SCHEMBL8635392 | 0.85 | L3MBTL1 (0.49) | KMT2AMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8632682 | 0.85 | KDM1A (0.46) | KMT2AMAPTL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL8627990 | 0.84 | HPGD (0.41) | KMT2AGAAMAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |