Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624605 | 0.93 | BRD4 (0.47) | BRD4CSF1RRAD52TACR1TDP2 | |
| SCHEMBL8628563 | 0.91 | BRD4 (0.42) | BRD4CSF1RRAD52TACR1DRD2 | |
| SCHEMBL8629280 | 0.90 | MITF (0.41) | BRD4RAD52GAAHTR6DRD2 | |
| SCHEMBL8625789 | 0.90 | BRD4 (0.43) | BRD4TDP2NSD2PLA2G1BATG4B | |
| SCHEMBL8627347 | 0.83 | MITF (0.39) | BRD4RAD52GAA | |
| SCHEMBL8625881 | 0.83 | BRD4 (0.45) | BRD4TDP2NSD2PLA2G1BATG4B | |
| Hydrochloric Acid SCHEMBL8625633 | 0.83 | BRD4 (0.38) | BRD4RAD52GAA | |
| SCHEMBL8630282 | 0.82 | PGAM1 (0.39) | BRD4 | |
| SCHEMBL8625656 | 0.81 | PGAM1 (0.41) | BRD4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8628439 | 0.81 | CCNA2 (0.37) | BRD4RAD52GAAHTR6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849912-A | Biphenyl derivatives | EISAI CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |