Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 2/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.45 |
| ▸ | KIT | P10721 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | ACLY | P53396 | 3/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627771 | 0.88 | ALDH1A1 (0.47) | PTGS2PTGS1AAK1NTRK1KIT | |
| SCHEMBL8632810 | 0.86 | STAT3 (0.42) | STAT3KITMAPK14SCN9ATUBB4A | |
| SCHEMBL8631045 | 0.86 | STAT3 (0.42) | STAT3AAK1PIK3CAACLYMAPK14 | |
| SCHEMBL8758715 | 0.83 | ALDH1A1 (0.43) | PTGS2PTGS1AAK1NTRK1KIT | |
| SCHEMBL8632208 | 0.81 | STAT3 (0.51) | STAT3TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8632663 | 0.81 | CYP17A1 (0.48) | NR3C1AAK1PIK3CACDK2MAPK14 | |
| SCHEMBL8631178 | 0.81 | STAT3 (0.47) | STAT3KITMAPK14 | |
| SCHEMBL8635055 | 0.81 | PTGS2 (0.48) | PTGS2PTGS1NR3C1STAT3ACLY | |
| SCHEMBL8659801 | 0.80 | STAT3 (0.69) | PTGS2PTGS1NR3C1STAT3ACLY | |
| SCHEMBL8630028 | 0.80 | ALDH1A1 (0.45) | AAK1NTRK1KITPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |