Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KIT | P10721 | 3/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NAT1 | P18440 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632810 | 0.89 | STAT3 (0.42) | ALDH1A1MCOLN3L3MBTL1MCL1FFAR4 | |
| SCHEMBL8758268 | 0.89 | PKM (0.42) | ALDH1A1MCOLN3L3MBTL1MCL1MAPT | |
| SCHEMBL8627771 | 0.88 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TSHRMAPTKIT | |
| SCHEMBL8632837 | 0.86 | LMNA (0.51) | ALDH1A1MCOLN3L3MBTL1MCL1FFAR4 | |
| SCHEMBL8628067 | 0.85 | SMN1; SMN2 (0.43) | ALDH1A1FFAR4TSHRCYTH2MAPT | |
| SCHEMBL8631345 | 0.85 | MCL1 (0.49) | ALDH1A1MCOLN3MCL1FFAR4TSHR | |
| SCHEMBL8632286 | 0.84 | KIT (0.45) | ALDH1A1MCOLN3MAPTKITPIK3CA | |
| SCHEMBL8758715 | 0.84 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTKITNTRK1 | |
| SCHEMBL8631080 | 0.82 | KMO (0.52) | PIK3CAHTT | |
| SCHEMBL8627628 | 0.82 | FFAR4 (0.44) | ALDH1A1MCOLN3L3MBTL1FFAR4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |