Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628285 | 0.70 | POLB (0.33) | PDE4DALDH1A1SMN1; SMN2CTSKLMNA | |
| SCHEMBL8632044 | 0.69 | POLB (0.33) | LMNAHTTMAPK1POLB | |
| SCHEMBL8630672 | 0.68 | KDM4E (0.44) | PDE4DALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL8626203 | 0.68 | LMNA (0.30) | ALDH1A1LMNAHTT | |
| SCHEMBL8625346 | 0.66 | HSD17B10 (0.47) | ALDH1A1SMN1; SMN2LMNAMAPK1CA12 | |
| SCHEMBL11416509 | 0.62 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2LMNAHTTMAPK1 | |
| SCHEMBL11419206 | 0.62 | LMNA (0.38) | ALDH1A1SMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL8629452 | 0.61 | CA12 (0.39) | PDE4DALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6354460 | 0.61 | CA12 (0.47) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL12951609 | 0.61 | MMP8 (0.54) | ALDH1A1SMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |