Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628308 | 0.80 | — | — | |
| SCHEMBL11416509 | 0.72 | ALDH1A1 (0.31) | POLBLMNAHTTMAPK1 | |
| SCHEMBL8628285 | 0.70 | POLB (0.33) | POLBLMNAHTT | |
| SCHEMBL8629455 | 0.69 | PDE4D (0.33) | POLBLMNAHTTMAPK1 | |
| SCHEMBL2441045 | 0.68 | CYP1A2 (0.38) | LMNAHTTMAPK1 | |
| SCHEMBL8626203 | 0.68 | LMNA (0.30) | LMNAHTT | |
| Hydrochloric Acid SCHEMBL3827092 | 0.65 | MAPK1 (0.35) | LMNAHTTMAPK1 | |
| SCHEMBL11419206 | 0.62 | LMNA (0.38) | POLBLMNAHTT | |
| SCHEMBL10620729 | 0.61 | GAA (0.50) | LMNAHTTMAPK1 | |
| SCHEMBL12951609 | 0.61 | MMP8 (0.54) | POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |