SCHEMBL8629624

SCHEMBL8629624

Sc1nncn1CCN1CCOCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.39
SIGMAR1 Q99720 2/20 0.37
POLB P06746 1/20 0.37
MAPK13 O15264 1/20 0.36
MAPK12 P53778 1/20 0.36
MAPK11 Q15759 1/20 0.36
MAPK14 Q16539 1/20 0.36
KDM4E B2RXH2 6/20 0.36
ALDH1A1 P00352 4/20 0.36
KEAP1 Q14145 1/20 0.36
HSD17B10 Q99714 3/20 0.36
LMNA P02545 2/20 0.36
HPGD P15428 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RCE1 Q9Y256 1/20 0.35
CXCR4 P61073 1/20 0.35
CNR1 P21554 1/20 0.35
USP2 O75604 1/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8983983 0.72 MAPK13 (0.39) SMN1; SMN2SIGMAR1POLBMAPK13MAPK12
SCHEMBL235080 0.67 KDM4E (0.65) SMN1; SMN2SIGMAR1POLBKDM4EALDH1A1
SCHEMBL3993816 0.66 LMNA (0.46) SMN1; SMN2SIGMAR1POLBKDM4EALDH1A1
SCHEMBL10913328 0.65 KDM4E (0.70) SMN1; SMN2SIGMAR1POLBKDM4EALDH1A1
SCHEMBL11856358 0.65 KDM4E (0.70) SMN1; SMN2SIGMAR1POLBKDM4EALDH1A1
SCHEMBL6015852 0.64 SMN1; SMN2 (0.41) SMN1; SMN2SIGMAR1POLBKDM4EALDH1A1
SCHEMBL3987440 0.64 KDM4E (0.38) SMN1; SMN2SIGMAR1POLBKDM4EALDH1A1
SCHEMBL17008888 0.63 SMN1; SMN2 (0.46) SMN1; SMN2SIGMAR1MAPK13MAPK12MAPK11
SCHEMBL8983962 0.63 KEAP1 (0.42) SMN1; SMN2SIGMAR1POLBALDH1A1KEAP1
SCHEMBL14553277 0.62 ALDH1A1 (0.51) SMN1; SMN2SIGMAR1POLBALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150287953-A1 TRANSPARENT ELECTRODE, ELECTRONIC DEVICE, AND ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
US-20150287953-A1 TRANSPARENT ELECTRODE, ELECTRONIC DEVICE, AND ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
US-RE35754-E FOR TREATING BACTERIAL INFECTIONS HOECHST AKTIENGESELLSCHAFT (DE) 1998-03-24 US disclosed
US-5710146-A ANTIBIOTICS FOR BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-20 US disclosed
US-5338658-A Nucleation agent FUJI PHOTO FILM CO., LTD. (JP) 1994-08-16 US disclosed
EP-0318987-B1 DIRECT POSITIVE PHOTOGRAPHIC LIGHTSENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1993-02-03 EP disclosed
EP-0276842-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1992-07-29 EP disclosed
US-5089490-A Cephem derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-18 US disclosed
EP-0450637-A2 Direct positive color image forming method FUJI PHOTO FILM CO., LTD. (JP) 1991-10-09 EP disclosed
US-5009993-A Having hydrophilic colloidal layers containing colloidal transition metals, or sulfides, tellurides or selenides of said metals; not previously fogged FUJI PHOTO FILM CO., LTD. (JP) 1991-04-23 US disclosed
US-4880727-A SILVER HALIDE EMULSIONS, COLLOIDS, MULTILAYER FUJI PHOTO FILM CO., LTD. (JP) 1989-11-14 US disclosed
US-4877723-A EMULSION LAYER CONTAINING AN ALKYNYL-SUBSTITUTED HETEROCYCLIC QUATERNARY AMMONIUM SALT; DIRECT POSITIVES; REVERSAL FUJI PHOTO FILM CO., LTD. (JP) 1989-10-31 US disclosed
US-4859579-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-08-22 US disclosed
EP-0318987-A1 Direct positive photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 1989-06-07 EP disclosed
EP-0315890-A1 Method for forming a direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1989-05-17 EP disclosed
EP-0303301-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-02-15 EP disclosed
EP-0276842-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-08-03 EP disclosed
US-4758556-A Cephem derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-19 US disclosed
EP-0267482-A2 Direct positive color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1988-05-18 EP disclosed
US-4278793-A ANTIBIOTICS, BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1981-07-14 US disclosed