SCHEMBL8629633

SCHEMBL8629633

O=C(O)c1cc(C2CC=CCC2)c(C(=O)O)c2c1CC2

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
AKR1C3 P42330 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12478008 0.80 ACMSD (0.41) MAPT
SCHEMBL253754 0.79 ACMSD (0.43) MAPT
SCHEMBL4566527 0.75 SCN9A (0.33) MAPT
SCHEMBL7119685 0.74 MAPT (0.32) MAPT
SCHEMBL4357324 0.71 RAB9A (0.43) MAPTAKR1C3
SCHEMBL754115 0.69 CYP1A2 (0.39) MAPTAKR1C3
SCHEMBL10369790 0.68 KDM4C (0.44) MAPT
SCHEMBL9510268 0.68 ALDH1A1 (0.41) MAPTAKR1C3
SCHEMBL4566639 0.67 ACMSD (0.43) MAPT
SCHEMBL9338883 0.66 CYP3A4 (0.39) MAPTAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711315-B1 A PROCESS FOR PREPARING HYDROLYTICALLY STABLE POLY(ETHYLENE-2,6-NAPHTHALENE DICARBOXYLATE) POLYMERS EASTMAN CHEM CO (US) 1999-06-02 EP disclosed
EP-0711315-A1 A PROCESS FOR PREPARING HYDROLYTICALLY STABLE POLY(ETHYLENE-2,6-NAPHTHALENE DICARBOXYLATE) POLYMERS EASTMAN CHEMICAL COMPANY (US) 1996-05-15 EP disclosed
EP-0539392-B1 Process for preparing mixtures of polycarbonate and poly(1,4-cyclohexenedimethylene terephthalate) with reduced undesirable colour formation. EASTMAN CHEM CO (US) 1995-05-10 EP disclosed
WO-1995003348-A1 A PROCESS FOR PREPARING HYDROLYTICALLY STABLE POLY(ETHYLENE-2,6-NAPHTHALENE DICARBOXYLATE) POLYMERS EASTMAN CHEMICAL COMPANY (US) 1995-02-02 WO disclosed
US-5321074-A Adding alkali metal salt in melt polymerization mixture EASTMAN CHEMICAL COMPANY (US) 1994-06-14 US disclosed
EP-0539392-A1 Mixtures of polycarbonate and poly(1,4-cyclohexenedimethylene terephthalate). EASTMAN KODAK CO (US) 1993-05-05 EP disclosed