Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CASR | P41180 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31314837 | 0.80 | CASR (0.47) | ALDH1A1SMN1; SMN2CASRKMT2AKDM4A | |
| SCHEMBL16675470 | 0.73 | LMNA (0.47) | ALDH1A1SMN1; SMN2KMT2AKDM4ALMNA | |
| SCHEMBL21084071 | 0.68 | CCR1 (0.58) | SMN1; SMN2KMT2ATSHRHSD17B10KDM4E | |
| SCHEMBL18654544 | 0.67 | DYRK1A (0.55) | SMN1; SMN2KMT2AKDM4ALMNATSHR | |
| SCHEMBL14359173 | 0.67 | SMN1; SMN2 (0.66) | ALDH1A1SMN1; SMN2KMT2ALMNATSHR | |
| SCHEMBL14198211 | 0.66 | MAPT (0.51) | ALDH1A1SMN1; SMN2KMT2ALMNATSHR | |
| SCHEMBL3924359 | 0.66 | TGFBR1 (0.46) | ALDH1A1SMN1; SMN2KMT2AKDM4ALMNA | |
| SCHEMBL8629665 | 0.64 | NR1I2 (0.39) | ALDH1A1SMN1; SMN2KMT2AKDM4ALMNA | |
| SCHEMBL8627702 | 0.64 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KMT2AKDM4ALMNA | |
| SCHEMBL25124961 | 0.64 | PDE10A (0.43) | ALDH1A1SMN1; SMN2KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1295071-A | Condensed imidezo-[1,2-a] pyridines | NEW JAPAN MEDICINE CO LTD (JP) | 2001-05-16 | — | — | CN | disclosed |
| CN-1064360-C | Fused imidazo [1, 2-a ] pyridines | SHINIPPON PHARMACEUTICAL INC (JP) | 2001-04-11 | — | — | CN | disclosed |
| CN-1182428-A | Fused imidazo [1, 2-alpha ] pyridines | SHINNIPPON PHARMACEUTICAL INC (JP) | 1998-05-20 | — | — | CN | disclosed |