Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.65 |
| ▸ | LTA4H | P09960 | 2/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.59 |
| ▸ | HTR1A | P08908 | 5/20 | 0.55 |
| ▸ | HTR1B | P28222 | 4/20 | 0.55 |
| ▸ | HTR1D | P28221 | 3/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907343 | 0.92 | HTR1A (0.66) | MTNR1AMTNR1BLTA4HPLA2G2AHTR1A | |
| SCHEMBL14907340 | 0.92 | HTR1A (0.66) | MTNR1AMTNR1BLTA4HPLA2G2AHTR1A | |
| SCHEMBL8881982 | 0.91 | MTNR1A (0.58) | MTNR1AMTNR1BLTA4HPLA2G2AHTR1A | |
| SCHEMBL8626837 | 0.91 | HTR1A (0.65) | MTNR1AMTNR1BLTA4HPLA2G2AHTR1A | |
| SCHEMBL8624581 | 0.90 | MTNR1A (0.57) | MTNR1AMTNR1BLTA4HPLA2G2AHTR1A | |
| SCHEMBL8880875 | 0.90 | MTNR1A (0.59) | MTNR1AMTNR1BLTA4HPLA2G2AHTR1A | |
| SCHEMBL8624381 | 0.90 | HTR1A (0.63) | MTNR1AMTNR1BLTA4HPLA2G2AHTR1A | |
| SCHEMBL8626639 | 0.89 | HTR1A (0.59) | MTNR1AMTNR1BLTA4HPLA2G2AHTR1A | |
| SCHEMBL8880324 | 0.89 | MTNR1A (0.60) | MTNR1AMTNR1BLTA4HPLA2G2AHTR1A | |
| SCHEMBL14961084 | 0.87 | TRPM8 (0.63) | MTNR1AMTNR1BLTA4HPLA2G2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666847-B1 | TRYPTAMINE ANALOGS WITH 5-HT1D SELECTIVITY | ALLELIX BIOPHARMA (CA) | 1998-06-17 | — | — | EP | disclosed |
| US-5496957-A | 5-HYDOXYTRYPTAMINE | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1996-03-05 | — | — | US | disclosed |
| EP-0666847-A1 | TRYPTAMINE ANALOGS WITH 5-HT1D SELECTIVITY | Allelix Biopharmaceuticals Inc. (CA) | 1995-08-16 | — | — | EP | disclosed |
| WO-1995006638-A1 | TRYPTAMINE ANALOGS WITH 5-HT1D SELECTIVITY | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1995-03-09 | — | — | WO | disclosed |