Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431778 | 0.85 | MAOA (0.42) | MAOANOX1L3MBTL1MEN1KMT2A | |
| SCHEMBL8633030 | 0.80 | KDM4E (0.31) | MEN1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL7395913 | 0.77 | GAA (0.35) | MEN1KMT2AADRA2ASLC6A2SLC6A4 | |
| SCHEMBL8630694 | 0.72 | HPGD (0.35) | MAOANOX1L3MBTL1MEN1KMT2A | |
| SCHEMBL628362 | 0.69 | MAOA (0.64) | MAOANOX1L3MBTL1MEN1KMT2A | |
| SCHEMBL7390458 | 0.68 | PDF (0.39) | MEN1KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL27430518 | 0.68 | MAOA (0.58) | MAOANOX1L3MBTL1MEN1KMT2A | |
| SCHEMBL7072232 | 0.67 | MAOA (0.62) | MAOANOX1L3MBTL1MEN1KMT2A | |
| SCHEMBL231247 | 0.67 | MAOA (1.00) | MAOANOX1L3MBTL1MEN1KMT2A | |
| SCHEMBL29377505 | 0.67 | MAOA (1.00) | MAOANOX1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811389-A | INHIBITING PLATELET AGGREGATION; BLOOD DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5811548-A | USEFUL AS RESEARCH TOOLS IN THE DETERMINATION OF BIOLOGICALLY ACTIVE PEPTIDE SEQUENCES | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |