Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629912 | 0.80 | MAOA (0.46) | KDM4EMEN1LMNAHTTKMT2A | |
| SCHEMBL7395913 | 0.75 | GAA (0.35) | KDM4EMEN1LMNAKMT2A | |
| SCHEMBL2082921 | 0.74 | LMNA (0.40) | MEN1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL3907030 | 0.71 | CYP2A6 (0.32) | MEN1LMNAKMT2A | |
| SCHEMBL7392294 | 0.69 | MAOA (0.56) | KDM4EMEN1LMNAPABPC1HTT | |
| SCHEMBL8633026 | 0.68 | BACE1 (0.40) | — | |
| SCHEMBL7431778 | 0.67 | MAOA (0.42) | MEN1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL7394096 | 0.66 | ALDH1A1 (0.33) | KDM4EMEN1LMNAPABPC1HTT | |
| SCHEMBL8635781 | 0.65 | TLR2 (0.35) | KDM4EMEN1LMNAPABPC1HTT | |
| SCHEMBL7429083 | 0.65 | SMYD2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811548-A | USEFUL AS RESEARCH TOOLS IN THE DETERMINATION OF BIOLOGICALLY ACTIVE PEPTIDE SEQUENCES | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5811389-A | INHIBITING PLATELET AGGREGATION; BLOOD DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |