Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 12/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | Q9HBH1 | 1/20 | 0.40 | |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398260 | 0.82 | AKR1B1 (0.38) | — | |
| SCHEMBL8632265 | 0.80 | DRD2 (0.41) | CDC25APPARGPDF | |
| Hydrochloric Acid SCHEMBL8629088 | 0.74 | PTGS2 (0.34) | — | |
| SCHEMBL7391256 | 0.71 | PDF (0.51) | CDC25APDFCES1 | |
| SCHEMBL7391109 | 0.66 | CDC25A (0.46) | CDC25ACES1 | |
| SCHEMBL11498516 | 0.66 | BID (0.55) | PPARG | |
| SCHEMBL3635173 | 0.65 | CDC25A (0.61) | CDC25ACES1 | |
| SCHEMBL30141987 | 0.65 | CDC25A (0.61) | CDC25ACES1 | |
| SCHEMBL27889168 | 0.64 | AKR1B1 (0.50) | — | |
| SCHEMBL28365729 | 0.64 | PDF (0.54) | CDC25APDFCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811548-A | USEFUL AS RESEARCH TOOLS IN THE DETERMINATION OF BIOLOGICALLY ACTIVE PEPTIDE SEQUENCES | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5811389-A | INHIBITING PLATELET AGGREGATION; BLOOD DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |
| CN-1086825-A | Three ring and tetracyclic compounds | HOFFMANN LA ROCHE (CH) | 1994-05-18 | — | — | CN | disclosed |