Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 8/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 2/20 | 0.36 |
| ▸ | Q9HBH1 | 1/20 | 0.36 | |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392981 | 0.86 | KCNA5 (0.41) | DRD2KCNA5SUCNR1 | |
| SCHEMBL8629919 | 0.80 | CDC25A (0.43) | PPARGCDC25APDF | |
| SCHEMBL7388853 | 0.79 | DRD2 (0.39) | DRD2CNR2CTSK | |
| SCHEMBL29430481 | 0.72 | KCNA5 (0.53) | KCNA5CTSK | |
| SCHEMBL825511 | 0.72 | KCNA5 (0.53) | KCNA5CTSK | |
| Hexane SCHEMBL21545362 | 0.69 | RIPK1 (0.44) | DRD2KCNA5CTSK | |
| SCHEMBL7393683 | 0.67 | DRD2 (0.37) | DRD2 | |
| SCHEMBL12663115 | 0.67 | KCNA5 (0.48) | KCNA5CTSK | |
| SCHEMBL7386864 | 0.67 | TLR8 (0.33) | PPARGCDC25APDF | |
| SCHEMBL20049207 | 0.67 | LMNA (0.48) | KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811389-A | INHIBITING PLATELET AGGREGATION; BLOOD DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5811548-A | USEFUL AS RESEARCH TOOLS IN THE DETERMINATION OF BIOLOGICALLY ACTIVE PEPTIDE SEQUENCES | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |