Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 6/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629945 | 0.90 | ACLY (0.43) | ACLYPI4KBSCN9APTGS2PTGS1 | |
| SCHEMBL8630468 | 0.89 | SMN1; SMN2 (0.50) | ACLYPI4KBPTGS2PTGS1HTR6 | |
| SCHEMBL8631946 | 0.89 | ACLY (0.39) | ACLYPI4KBSCN9APTGS2PTGS1 | |
| SCHEMBL8630165 | 0.89 | ACLY (0.39) | ACLYPI4KBSCN9APTGS2PTGS1 | |
| SCHEMBL8631722 | 0.89 | PPARA (0.41) | ACLYPI4KBSCN9APTGS2PTGS1 | |
| SCHEMBL8630396 | 0.87 | PI4KB (0.44) | PI4KBPTGS2PTGS1 | |
| SCHEMBL8629870 | 0.86 | NPC1 (0.39) | ACLYPI4KBSCN9APTGS2PTGS1 | |
| SCHEMBL8635623 | 0.85 | PI4KB (0.44) | ACLYPI4KBPTGS2PTGS1HTR6 | |
| SCHEMBL8635028 | 0.85 | PI4KB (0.40) | ACLYPI4KBPTGS2PTGS1HTR6 | |
| SCHEMBL8635601 | 0.84 | ACLY (0.46) | ACLYPI4KBSCN9APTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |