Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630396 | 0.91 | PI4KB (0.44) | PI4KBMAPTPTGS1PTGS2 | |
| SCHEMBL8630468 | 0.89 | SMN1; SMN2 (0.50) | PI4KBMAPTHTR6PTGS1PTGS2 | |
| SCHEMBL8632918 | 0.89 | PI4KB (0.41) | PI4KBMAPTHTR6KDRPTGS1 | |
| SCHEMBL8632809 | 0.89 | PI4KB (0.42) | PI4KBMAPTHTR6KDRPTGS1 | |
| SCHEMBL8634716 | 0.88 | PI4KB (0.42) | PI4KBMAPTHTR6KDRPTGS1 | |
| SCHEMBL8631464 | 0.87 | PI4KB (0.40) | PI4KBMAPTHTR6KDRPTGS1 | |
| SCHEMBL8631050 | 0.87 | PTGS2 (0.42) | PI4KBMAPTHTR6KDRPTGS1 | |
| SCHEMBL8629938 | 0.85 | ACLY (0.41) | PI4KBHTR6PTGS1PTGS2ACLY | |
| SCHEMBL8635028 | 0.85 | PI4KB (0.40) | PI4KBMAPTHTR6PTGS1PTGS2 | |
| SCHEMBL8631588 | 0.82 | GAA (0.47) | MAPTPTGS2ALDH1A1NMT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |