Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629943 | 0.92 | MAPT (0.50) | HTTMAPTTSHRKMT2ANPSR1 | |
| SCHEMBL5193130 | 0.82 | MAPT (0.48) | HTTSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL8626823 | 0.81 | MAPT (0.64) | HTTSMN1; SMN2MAPTTSHRKMT2A | |
| SCHEMBL8628976 | 0.78 | ALDH1A1 (0.47) | HTTSMN1; SMN2MAPTTSHRKMT2A | |
| SCHEMBL8540029 | 0.76 | MAPT (0.48) | HTTSMN1; SMN2MAPTTSHRKMT2A | |
| SCHEMBL8628783 | 0.75 | RAB9A (0.49) | HTTSMN1; SMN2MAPTTSHRKMT2A | |
| SCHEMBL8627862 | 0.75 | ALDH1A1 (0.46) | HTTSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL8628972 | 0.74 | ALDH1A1 (0.44) | HTTMAPTTSHRKMT2ANPSR1 | |
| SCHEMBL8630090 | 0.73 | NTRK1 (0.46) | HTTSMN1; SMN2MAPTTSHRKMT2A | |
| SCHEMBL8873905 | 0.73 | MAPT (0.41) | HTTSMN1; SMN2MAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847126-A | N-azinyl-N'-(het) arylsulphonyl-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0645386-B1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| US-5696257-A | INTERMEDIATES FOR HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| US-5580842-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| US-5476936-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-19 | — | — | US | disclosed |
| EP-0645386-A1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1995-03-29 | — | — | EP | disclosed |