Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828390 | 0.86 | SIGMAR1 (0.70) | SIGMAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL9155641 | 0.85 | SIGMAR1 (0.73) | SIGMAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL7972498 | 0.83 | SIGMAR1 (0.72) | SIGMAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL7371550 | 0.78 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL1952604 | 0.78 | ADRA2C (0.52) | — | |
| SCHEMBL11812654 | 0.77 | NPC1 (0.46) | — | |
| SCHEMBL11806521 | 0.77 | NPC1 (0.46) | — | |
| SCHEMBL16994453 | 0.77 | SIGMAR1 (0.73) | SIGMAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL11104325 | 0.76 | SIGMAR1 (0.72) | SIGMAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL11134428 | 0.76 | SIGMAR1 (0.96) | SIGMAR1SLC6A2SLC6A4SLC6A3AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753714-A | ANTIPROTOZOA AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1998-05-19 | — | — | US | disclosed |
| US-5719193-A | Method of potentiating cell-mediated immunity utilizing polyamine derivatives | MERRELL PHARMACEUTICALS, INC. (US) | 1998-02-17 | — | — | US | disclosed |