Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ARG1 | P05089 | 5/20 | 0.47 |
| ▸ | ARG2 | P78540 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630883 | 0.98 | CYP2D6 (0.47) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| Lithium Ion SCHEMBL8630884 | 0.80 | ALDH1A1 (0.44) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| SCHEMBL8633224 | 0.77 | MAPT (0.44) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| Hydrochloric Acid SCHEMBL11725592 | 0.76 | ARG1 (0.46) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| SCHEMBL27911982 | 0.75 | ARG1 (0.45) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| SCHEMBL8630075 | 0.75 | MAPT (0.42) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| Hydrochloric Acid SCHEMBL27966524 | 0.73 | ARG1 (0.50) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| SCHEMBL7858744 | 0.73 | CA12 (0.42) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| SCHEMBL11801318 | 0.73 | ARG1 (0.43) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| Oxalic Acid SCHEMBL27268471 | 0.72 | SMN1; SMN2 (0.60) | MAPK1CYP1A2SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| EP-0667850-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS. | DOMPE FARMACEUTICI SPA (IT) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |