Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Formaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL29980301 | 0.96 | CA1 (0.57) | CA1CA2CA9F2PRSS1 | |
| Formaldehyde SCHEMBL27729297 | 0.96 | CA1 (0.57) | CA1CA2CA9F2PRSS1 | |
| Formaldehyde SCHEMBL29979739 | 0.96 | CA1 (0.57) | CA1CA2CA9F2PRSS1 | |
| Formaldehyde SCHEMBL117836 | 0.96 | CA1 (0.57) | CA1CA2CA9F2PRSS1 | |
| Potassium Ion SCHEMBL29414602 | 0.96 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| Potassium Ion SCHEMBL10962719 | 0.96 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| Potassium Ion SCHEMBL1305040 | 0.96 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| Potassium Ion SCHEMBL5834588 | 0.94 | CA1 (0.59) | CA1CA2CA9F2PRSS1 | |
| Potassium Ion SCHEMBL28244539 | 0.94 | CA1 (0.59) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL4886341 | 0.92 | CA1 (0.61) | CA1CA2CA9F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110635115-B | Nano-silicon/graphite phase carbon nitride/graphite composite negative electrode material and preparation method thereof | 东莞东阳光科研发有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-110564468-B | Environment-friendly coal water slurry additive and application thereof in preparation process of superfine-grinding high-concentration coal slurry in coal chemical industry | 常州中南化工有限公司 | 2021-10-15 | — | — | CN | claimed |
| CN-110564467-B | Environment-friendly coal water slurry additive and application thereof in coal water slurry waste blending preparation process | 常州中南化工有限公司 | 2021-10-15 | — | — | CN | claimed |
| CN-110635115-A | Nano-silicon/graphite phase carbon nitride/graphite composite negative electrode material and preparation method thereof | 东莞东阳光科研发有限公司 | 2019-12-31 | — | — | CN | claimed |
| CN-110564468-A | Environment-friendly coal water slurry additive and application thereof in preparation process of superfine-grinding high-concentration coal slurry in coal chemical industry | 常州中南化工有限公司 | 2019-12-13 | — | — | CN | claimed |
| CN-110564467-A | Efficient and environment-friendly coal water slurry additive and application thereof in coal water slurry waste blending preparation process | 常州中南化工有限公司 | 2019-12-13 | — | — | CN | claimed |
| EP-0583443-B1 | MAKING FLOWABLE ALKALI OR AMMONIUM THIOSULFATE OR SULFITE AND ITS PRODUCT-BY-PROCESS | FUJI HUNT PHOTO CHEM (BE) | 1998-11-04 | — | — | EP | claimed |
| US-RE35795-E | PHOTOGRAPHIC FIXATIVES | FUJI HUNT PHOTOGRAPHIC CHEMICALS, INC. (US) | 1998-05-12 | — | — | US | claimed |
| EP-0583443-A4 | MAKING FLOWABLE ALKALI OR AMMONIUM THIOSULFATE OR SULFITE AND ITS PRODUCT-BY-PROCESS | FUJI HUNT PHOTO CHEM (BE) | 1994-07-27 | — | — | EP | claimed |
| US-5328814-A | Containing a dry alkali metal arylsulfonate.formaldehyde | FUJI HUNT PHOTOGRAPHIC CHEMICALS, INC. (US) | 1994-07-12 | — | — | US | claimed |
| EP-0583443-A1 | MAKING FLOWABLE ALKALI OR AMMONIUM THIOSULFATE OR SULFITE AND ITS PRODUCT-BY-PROCESS | FUJI HUNT PHOTOGRAPHIC CHEMICALS, N.V. (BE) | 1994-02-23 | — | — | EP | claimed |
| US-5270154-A | Method of making flowable alkaline thiosulfate/alkaline sulfite and the product thereof | FUJI HUNT PHOTOGRAPHIC CHEMICALS INC. (US) | 1993-12-14 | — | — | US | claimed |
| WO-1993015437-A1 | MAKING FLOWABLE ALKALI OR AMMONIUM THIOSULFATE OR SULFITE AND ITS PRODUCT-BY-PROCESS | FUJI HUNT PHOTOGRAPHIC CHEMICALS, INC. (US) | 1993-08-05 | — | — | WO | claimed |
| US-4662943-A | Cement compositions containing a polysaccharide and a salt and method of cementing casing in a well | CHEVRON RESEARCH COMPANY (US) | 1987-05-05 | — | — | US | claimed |
| US-4573534-A | Cement compositions and method of cementing casing in a well | GULF OIL CORPORATION (US) | 1986-03-04 | — | — | US | claimed |
| US-4462836-A | MIXTURE OF HYDROXYALKYL CELLULOSE ETHERS, CEMENT, A POLYSACCHARIDE AND A DISPERSANT | GULF OIL CORPORATION (US) | 1984-07-31 | — | — | US | claimed |
| US-4462837-A | MIXTURE OF HYDROXYALKYL CELLULOSE ETHERS, CEMENT AND A DISPERSANT | GULF OIL CORPORATION (US) | 1984-07-31 | — | — | US | claimed |
| CN-117133907-B | Carbon-coated silicon composite material and preparation method and application thereof | 琥崧智能装备(太仓)有限公司 | 2024-01-26 | — | — | CN | disclosed |
| US-4462837-A | MIXTURE OF HYDROXYALKYL CELLULOSE ETHERS, CEMENT AND A DISPERSANT | GULF OIL CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |
| US-4041193-A | APPLYING AN ADHESIVE CONTAINING A SODIUM OR POTASSIUM SALT OF NAPHTHALENESULFONATE-FORMALDEHYDE CONDENSATE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-09 | — | — | US | disclosed |