Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 11/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634659 | 0.95 | MMP2 (0.33) | SLC10A2KDM1AMAOAMAOBOPRM1 | |
| SCHEMBL8631964 | 0.94 | MMP2 (0.35) | KDM1AMAOAMAOBOPRM1OPRL1 | |
| SCHEMBL8632114 | 0.91 | KDM1A (0.38) | SLC10A2KDM1AMAOAMAOB | |
| SCHEMBL8634390 | 0.84 | KDM1A (0.35) | KDM1AMAOAMAOB | |
| SCHEMBL9262727 | 0.78 | SLC10A2 (0.32) | SLC10A2KDM1AMAOAMAOB | |
| SCHEMBL8630991 | 0.75 | LTA4H (0.34) | — | |
| SCHEMBL10337714 | 0.73 | SLC10A2 (0.32) | SLC10A2KDM1AMAOAMAOB | |
| SCHEMBL10604204 | 0.73 | SLC10A2 (0.34) | SLC10A2KDM1AMAOAMAOBOPRM1 | |
| SCHEMBL10527595 | 0.72 | MMP2 (0.38) | SLC10A2KDM1AMAOAMAOBOPRM1 | |
| SCHEMBL9313274 | 0.72 | KDM1A (0.35) | SLC10A2KDM1AMAOAMAOBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449015-B1 | Difluoromethyl compounds and liquid criystal medium | MERCK PATENT GMBH (DE) | 1998-07-01 | — | — | EP | disclosed |
| EP-0449015-A2 | Difluoromethyl compounds and liquid criystal medium | MERCK PATENT GmbH (DE) | 1991-10-02 | — | — | EP | disclosed |