Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.35 |
| ▸ | MAOA | P21397 | 7/20 | 0.35 |
| ▸ | MAOB | P27338 | 7/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632114 | 0.87 | KDM1A (0.38) | KDM1AMAOAMAOBHTR2AHTR2C | |
| SCHEMBL8630877 | 0.84 | SLC10A2 (0.34) | KDM1AMAOAMAOB | |
| SCHEMBL8634659 | 0.83 | MMP2 (0.33) | KDM1AMAOAMAOB | |
| SCHEMBL8631964 | 0.82 | MMP2 (0.35) | KDM1AMAOAMAOB | |
| SCHEMBL8630919 | 0.76 | HTR2A (0.30) | HTR2AHTR2CHTR2B | |
| SCHEMBL8627301 | 0.73 | OPRM1 (0.32) | — | |
| SCHEMBL8462340 | 0.73 | KDM1A (0.38) | KDM1AMAOAMAOBHTR2AHTR2C | |
| SCHEMBL20456224 | 0.73 | KDM1A (0.46) | KDM1AMAOAMAOBHTR2AHTR2C | |
| SCHEMBL8630991 | 0.71 | LTA4H (0.34) | — | |
| Propane SCHEMBL23045273 | 0.71 | KDM1A (0.43) | KDM1AMAOAMAOBHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449015-B1 | Difluoromethyl compounds and liquid criystal medium | MERCK PATENT GMBH (DE) | 1998-07-01 | — | — | EP | disclosed |
| EP-0449015-A2 | Difluoromethyl compounds and liquid criystal medium | MERCK PATENT GmbH (DE) | 1991-10-02 | — | — | EP | disclosed |