Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774639 | 0.84 | DDB1 (0.41) | DHFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL5702480 | 0.84 | DDB1 (0.41) | DHFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4381658 | 0.84 | DHFR (0.45) | DHFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL3500438 | 0.83 | TNK2 (0.44) | DHFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6624255 | 0.83 | DHFR (0.55) | DHFRNPC1RAB9AHSD11B1KDM4C | |
| SCHEMBL813805 | 0.82 | NPC1 (0.46) | DHFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL863094 | 0.82 | DHFR (0.39) | DHFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL5702491 | 0.82 | MEN1 (0.40) | DHFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL883393 | 0.81 | DHFR (0.41) | DHFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL862862 | 0.81 | MEN1 (0.43) | DHFRNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143366-B2 | Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same | BIOCON LIMITED (IN) | 2012-03-27 | — | — | US | disclosed |
| US-7335751-B2 | Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same | BIOCON LIMITED (IN) | 2008-02-26 | — | — | US | disclosed |