Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 3/20 | 0.38 |
| ▸ | EDNRB | P24530 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634282 | 0.92 | EDNRA (0.38) | PPARAEDNRAEDNRBPTGS2PTGS1 | |
| SCHEMBL8631961 | 0.89 | PTGS2 (0.38) | EDNRAEDNRBPTGS2 | |
| SCHEMBL8631745 | 0.89 | PTGS2 (0.41) | PPARAPTGS2PTGS1PI4KBHTR6 | |
| SCHEMBL8635104 | 0.88 | PPARA (0.39) | PPARAPTGS2PTGS1PI4KBACLY | |
| SCHEMBL8630562 | 0.87 | CCR4 (0.42) | PPARAPTGS2PTGS1PI4KBPDE4B | |
| SCHEMBL8631658 | 0.87 | EDNRB (0.42) | EDNRAEDNRBPTGS2 | |
| SCHEMBL8629545 | 0.86 | NPC1 (0.41) | PPARAPTGS2PTGS1ACLYHTR6 | |
| SCHEMBL8629013 | 0.85 | PPARA (0.39) | PPARAPTGS2PTGS1PI4KBACLY | |
| SCHEMBL8631722 | 0.85 | PPARA (0.41) | PPARAPTGS2PTGS1PI4KBACLY | |
| SCHEMBL8631761 | 0.85 | PTGS2 (0.44) | PPARAEDNRAPTGS2PTGS1PI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |