Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629095 | 0.93 | MAPT (0.39) | PTGS2PPARASCN9APTGS1SMN1; SMN2 | |
| SCHEMBL8630562 | 0.91 | CCR4 (0.42) | PTGS2PPARAPTGS1PI4KB | |
| SCHEMBL8629955 | 0.91 | MAPT (0.46) | PTGS2PPARASCN9APTGS1SMN1; SMN2 | |
| SCHEMBL8631761 | 0.89 | PTGS2 (0.44) | PTGS2PPARAPTGS1HTR6PI4KB | |
| SCHEMBL8631722 | 0.89 | PPARA (0.41) | PTGS2PPARASCN9APTGS1HTR6 | |
| SCHEMBL8629013 | 0.89 | PPARA (0.39) | PTGS2PPARASCN9APTGS1MAPT | |
| SCHEMBL8630945 | 0.89 | PPARA (0.39) | PTGS2PPARAPTGS1HTR6PI4KB | |
| SCHEMBL8635104 | 0.89 | PPARA (0.39) | PTGS2PPARASCN9APTGS1MEN1 | |
| SCHEMBL8629750 | 0.88 | MAPT (0.46) | PTGS2SCN9APTGS1SMN1; SMN2MEN1 | |
| SCHEMBL8630468 | 0.88 | SMN1; SMN2 (0.50) | PTGS2PTGS1SMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |