Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837167 | 0.79 | ALDH1A1 (0.53) | ALDH1A1LMNARAB9ANPC1TDP1 | |
| SCHEMBL8631119 | 0.79 | DAO (0.53) | ALDH1A1LMNARAB9ANPC1TDP1 | |
| SCHEMBL8705579 | 0.79 | DAO (0.53) | ALDH1A1LMNARAB9ANPC1TDP1 | |
| SCHEMBL1750114 | 0.76 | HDAC8 (0.45) | ALDH1A1LMNARAB9ANPC1TDP1 | |
| SCHEMBL8628173 | 0.75 | RAB9A (0.36) | ALDH1A1LMNARAB9ANPC1TDP1 | |
| SCHEMBL10935869 | 0.74 | KDM4E (0.38) | ALDH1A1LMNATDP1MAPTL3MBTL1 | |
| SCHEMBL8630112 | 0.73 | GAA (0.51) | ALDH1A1RAB9ANPC1TDP1SMN1; SMN2 | |
| SCHEMBL8630018 | 0.73 | ALDH1A1 (0.65) | ALDH1A1LMNARAB9ANPC1TDP1 | |
| SCHEMBL1674356 | 0.72 | — | — | |
| SCHEMBL7217724 | 0.71 | L3MBTL1 (0.48) | ALDH1A1LMNARAB9ANPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840917-A | ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |