Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 3/20 | 0.38 |
| ▸ | RHOA | P61586 | 3/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 3/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.32 |
| ▸ | RELA | Q04206 | 3/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
| ▸ | XPO1 | O14980 | 1/20 | 0.30 |
| ▸ | ATF1 | P18846 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408424 | 0.90 | HTT (0.38) | RHOCRHOAHTTSCN9AALDH1A1 | |
| SCHEMBL8659999 | 0.87 | HTT (0.37) | RHOCRHOAHTTSCN9A | |
| SCHEMBL7982287 | 0.85 | HDAC1 (0.36) | HTTALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL8062091 | 0.84 | RHOC (0.59) | RHOCRHOASCN9AMRGPRX4 | |
| SCHEMBL7965854 | 0.84 | HTT (0.35) | RHOCRHOAHTTSCN9A | |
| SCHEMBL7979390 | 0.83 | SCN8A (0.38) | RHOCRHOAHTTSCN9A | |
| SCHEMBL7979279 | 0.83 | MAPT (0.36) | RHOCRHOAHTTSCN9AALDH1A1 | |
| SCHEMBL7073001 | 0.83 | PRKAB2 (0.38) | RHOCRHOAALDH1A1LMNAHPGD | |
| SCHEMBL7965745 | 0.83 | MAPT (0.35) | RHOCRHOAHTTSCN9AALDH1A1 | |
| SCHEMBL8659785 | 0.82 | PLAU (0.39) | HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824514-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-02-25 | — | — | EP | disclosed |