Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 6/20 | 0.42 |
| ▸ | FEN1 | P39748 | 6/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628069 | 0.87 | F10 (0.35) | PTGS2PTGS1F10PTGES2 | |
| SCHEMBL8629321 | 0.86 | PTGS2 (0.59) | ALOX5APFEN1PTGS2PTGS1 | |
| SCHEMBL8631176 | 0.86 | PTGS2 (0.46) | PTGS2PTGS1PTGES2 | |
| SCHEMBL8632812 | 0.84 | ALOX5AP (0.47) | ALOX5APFEN1PTGS2PTGS1F10 | |
| SCHEMBL7779676 | 0.83 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL8656979 | 0.82 | PTGS2 (0.51) | ALOX5APFEN1PTGS2PTGS1F10 | |
| SCHEMBL8632216 | 0.81 | SCN9A (0.46) | F10 | |
| SCHEMBL8657330 | 0.80 | PTGS2 (0.51) | ALOX5APFEN1PTGS2PTGS1F10 | |
| SCHEMBL8631181 | 0.80 | PTGS2 (0.50) | ALOX5APFEN1PTGS2PTGS1 | |
| SCHEMBL8629397 | 0.80 | ALOX5AP (0.40) | ALOX5APFEN1PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |