Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 11/20 | 0.47 |
| ▸ | FEN1 | P39748 | 11/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630031 | 0.89 | PTGS2 (0.41) | ALOX5APFEN1PTGS1PTGS2F10 | |
| SCHEMBL8629321 | 0.86 | PTGS2 (0.59) | ALOX5APFEN1PTGS1PTGS2 | |
| SCHEMBL8629486 | 0.84 | ALOX5AP (0.44) | ALOX5APFEN1F10TRPV1 | |
| SCHEMBL7778071 | 0.84 | PTGS2 (0.53) | PTGS1PTGS2 | |
| SCHEMBL8631047 | 0.84 | ALOX5AP (0.42) | ALOX5APFEN1PTGS1PTGS2F10 | |
| SCHEMBL8627772 | 0.83 | PTGS2 (0.47) | PTGS1PTGS2F10 | |
| SCHEMBL8631181 | 0.83 | PTGS2 (0.50) | ALOX5APFEN1PTGS1PTGS2TRPV1 | |
| SCHEMBL8632840 | 0.83 | LRRK2 (0.42) | PTGS1PTGS2F10 | |
| SCHEMBL8631346 | 0.82 | NPC1 (0.40) | ALOX5APFEN1 | |
| SCHEMBL8660031 | 0.81 | ALOX5AP (0.53) | ALOX5APFEN1PTGS1PTGS2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |