Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.66 |
| ▸ | MAPT | P10636 | 9/20 | 0.66 |
| ▸ | NPC1 | O15118 | 8/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631382 | 0.80 | OGG1 (0.70) | RAB9AMAPTNPC1LMNAGAA | |
| SCHEMBL9178739 | 0.80 | MCL1 (0.74) | RAB9AMAPTNPC1LMNAGAA | |
| SCHEMBL8709448 | 0.80 | RAB9A (0.41) | RAB9AMAPTNPC1LMNAGAA | |
| SCHEMBL5023231 | 0.78 | MCL1 (0.77) | RAB9AMAPTNPC1LMNAGAA | |
| SCHEMBL415459 | 0.78 | MCL1 (0.77) | RAB9AMAPTNPC1LMNAGAA | |
| SCHEMBL417349 | 0.78 | MCL1 (1.00) | RAB9AMAPTNPC1LMNAGAA | |
| SCHEMBL5023563 | 0.77 | MCL1 (0.70) | RAB9AMAPTNPC1LMNAGAA | |
| Hydrochloric Acid SCHEMBL11398368 | 0.77 | MCL1 (0.97) | RAB9AMAPTNPC1LMNAGAA | |
| SCHEMBL14615371 | 0.76 | MCL1 (0.68) | RAB9AMAPTNPC1LMNAGAA | |
| SCHEMBL13659630 | 0.74 | MCL1 (0.70) | RAB9AMAPTNPC1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840917-A | ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |