Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | CISD2 | Q8N5K1 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631381 | 0.82 | OGG1 (0.43) | RAB9AMAPTNPC1LMNAGAA | |
| SCHEMBL8631349 | 0.80 | RAB9A (0.66) | RAB9AMAPTNPC1LMNAGAA | |
| SCHEMBL8634456 | 0.68 | MAPT (0.41) | RAB9AMAPTNPC1LMNAGAA | |
| SCHEMBL8633480 | 0.67 | DAO (0.56) | RAB9AMAPTNPC1GAASMN1; SMN2 | |
| SCHEMBL8587274 | 0.66 | CCNB2 (0.33) | RAB9AMAPTNPC1LMNAGAA | |
| SCHEMBL11426548 | 0.66 | SMN1; SMN2 (0.50) | RAB9AMAPTNPC1MCL1SMN1; SMN2 | |
| SCHEMBL8656312 | 0.65 | ALDH1A1 (0.59) | RAB9ANPC1LMNAGAASMN1; SMN2 | |
| SCHEMBL6375945 | 0.64 | KMT2A (0.53) | RAB9AMAPTNPC1LMNAGAA | |
| SCHEMBL8634421 | 0.64 | DAO (0.55) | RAB9AMAPTNPC1LMNASMN1; SMN2 | |
| SCHEMBL8630205 | 0.64 | ALDH1A1 (0.37) | RAB9AMAPTNPC1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |