Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627799 | 0.90 | PTGS2 (0.49) | PTGS2KMT2AMAPTSMN1; SMN2PPARG | |
| SCHEMBL8631337 | 0.89 | PTGS2 (0.50) | PTGS2KMT2AMAPTSMN1; SMN2TDP1 | |
| SCHEMBL8631550 | 0.88 | PTGS2 (0.58) | PTGS2KMT2AMAPTPOLBMEN1 | |
| SCHEMBL8634609 | 0.88 | KMT2A (0.45) | PTGS2KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL8629761 | 0.87 | PTGS2 (0.48) | PTGS2KMT2AMAPTPOLBMEN1 | |
| SCHEMBL8634392 | 0.87 | PTGS2 (0.48) | PTGS2KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL8631761 | 0.87 | PTGS2 (0.44) | PTGS2CYP2C9 | |
| SCHEMBL8631438 | 0.87 | CYP1A2 (0.46) | PTGS2KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL8631944 | 0.85 | KMT2A (0.44) | KMT2AGAAMAPTSMN1; SMN2TDP1 | |
| SCHEMBL8631393 | 0.85 | KMT2A (0.42) | KMT2AGAAMAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |