Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | NOS2 | P35228 | 3/20 | 0.41 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616188 | 0.74 | GAA (0.50) | NOS3NOS1NOS2KDM4ESMN1; SMN2 | |
| SCHEMBL251167 | 0.73 | PNMT (0.44) | NOS3NOS1NOS2PNMTKDM4E | |
| SCHEMBL28893753 | 0.71 | KDM4E (0.43) | PNMTKDM4ESMN1; SMN2DPP4BRD4 | |
| SCHEMBL2904188 | 0.69 | KDM4E (0.43) | PNMTKDM4ESMN1; SMN2DPP4 | |
| SCHEMBL5700249 | 0.69 | HTR3E (0.47) | NOS3NOS1NOS2SMN1; SMN2TAAR1 | |
| SCHEMBL8109115 | 0.69 | L3MBTL1 (0.49) | PNMTKDM4ESMN1; SMN2DPP4BRD4 | |
| SCHEMBL27541226 | 0.69 | NOS3 (0.54) | NOS3NOS1NOS2PNMTSIGMAR1 | |
| Bicarbonate SCHEMBL27658688 | 0.69 | KDM4E (0.53) | PNMTKDM4ESMN1; SMN2DPP4CYP1A2 | |
| Bicarbonate SCHEMBL31055577 | 0.69 | KDM4E (0.53) | PNMTKDM4ESMN1; SMN2DPP4CYP1A2 | |
| Bicarbonate SCHEMBL27658689 | 0.69 | KDM4E (0.53) | PNMTKDM4ESMN1; SMN2DPP4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801242-A | Process for making quinolonyl lactam antimicrobials and novel intermediate compounds | THE PROCTER & GAMBLE COMPANY (US) | 1998-09-01 | — | — | US | disclosed |
| US-5703231-A | Process for making antimicrobial compounds | THE PROCTER & GAMBLE COMPANY (US) | 1997-12-30 | — | — | US | disclosed |